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J Alzheimers Dis 15, 289-301. Duara R, Barker W, Loewenstein D, Bain L (2009) The foundation for disease-modifying treatments for Alzheimer’s disease: The Sixth Annual Mild Cognitive Impairment Symposium. Alzheimers Dement 5, 66-74. Panza F, Solfrizzi V, Frisardi V, Capurso C, D’Introno A, Colacicco AM, Vendemiale G, Capurso A, Imbimbo BP (2009) Disease-modifying approach to the treatment method of Alzheimer’s condition: From alpha-secretase activators to gamma-secretase inhibitors and modulators. Nat Rev Drug Discov 9, 387-398. Frisardi V, Solfrizzi V, Imbimbo PB, Capurso C, D’Introno A, Colacicco AM, Vendemiale G, Seripa D, Pilotto A, Capurso A, Panza F (2010) Towards sickness-modifying therapy of Alzheimer’s condition: Drugs focusing on betaamyloid. fifty five Panza F, Frisardi V, Solfrizzi V, Imbimbo BP, Logroscino G, Santamato A, Greco A, Seripa D, Pilotto A (2012) Immunotherapy for Alzheimer’s sickness: From anti-beta-amyloid to tau-based mostly immunization methods. J Neurosci 26, 662-670. Bachstetter Ad, Norris CM, Sompol P, Wilcock DM, Goulding D, Neltner JH, St CD, Watterson DM, Van Eldik LJ (2012) Early stage drug treatment that normalizes proinflammatory cytokine output attenuates synaptic dysfunction in a mouse product that reveals age-dependent progression of Alzheimer’s sickness-connected pathology. Arterioscler Thromb Vasc Biol 32, 2503-2509. Anonymous (2011) Rvx 208. Drugs R D 11, 207-213. Nicholls SJ, Gordon A, Johannson J, Ballantyne CM, Barter PJ, Brewer HB, Kastelein JJ, Wong NC, Borgman MR, Nissen SE (2012) ApoA-I induction as a possible cardioprotective method: Rationale for the Sustain and Assure reports.

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